An Insight into the Synthesis of 2-Bromo-1-[4-(Methylsulfonyl) Phenyl]-1-Ethanone

Jiangsu Jingye Pharmaceutical is proud to present a detailed account of the production process for one of our flagship compounds, 2-Bromo-1-[4-(Methylsulfonyl) Phenyl]-1-Ethanone, a versatile intermediate in pharmaceutical synthesis.

Introduction:

2-Bromo-1-[4-(Methylsulfonyl) Phenyl]-1-Ethanone, known for its utility in the synthesis of carbonyl compounds, is a pivotal intermediate in the manufacture of various pharmaceuticals, APIs, and custom synthesis chemicals. With a CAS No. of 50413-24-6 and a molecular weight of 277.14, this compound is synthesized through a meticulous process that ensures high quality and purity.

Synthesis Process:

The synthesis of 2-Bromo-1-[4-(Methylsulfonyl) Phenyl]-1-Ethanone involves several key steps:

1. Activation of the Phenyl Ring: The process begins with the activation of the phenyl ring to allow for subsequent reactions.

2. Sulfonylation: The introduction of the methylsulfonyl group occurs through a sulfonylation reaction, utilizing dimethyl sulfate as a sulfonylating agent.

3. Bromination: The alpha position of the acetophenone is then subjected to bromination, employing bromine as the halogenating agent.

4. Purification: The crude product undergoes a rigorous purification process, including recrystallization and chromatography, to achieve the desired level of purity.

Quality Assurance:

Our product stands out in the market due to its superior quality, backed by stringent quality control measures. Each batch is tested to ensure it meets our high standards for purity and consistency.

Applications:

This compound finds extensive use in the pharmaceutical industry, serving as an intermediate for the synthesis of various active pharmaceutical ingredients (APIs). Its versatility also makes it suitable for custom synthesis and chemical research.

Conclusion:

At Jiangsu Jingye Pharmaceutical, we are committed to providing our clients with high-quality chemical intermediates like 2-Bromo-1-[4-(Methylsulfonyl) Phenyl]-1-Ethanone. Our dedication to excellence is reflected in our competitive pricing, fast delivery, and quick response to customer inquiries.For more information or to place an order, please contact us:email:guml@depeichem.com/shiyf@depeichem.com. We are eager to assist you with your chemical and pharmaceutical needs.